Stay at Best Western On the River in Hannibal, MO. Enjoy free breakfast, indoor pool, hot tub, LGBTQ+ friendly amenities, and easy access to Mark Twain attractions.
Guests appreciate comfortable rooms and helpful staff, especially the proximity to Mark Twain attractions. Some minor drawbacks include parking challenges and mixed feedback on housekeeping.
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Rooms, shared spaces, dining and exterior — grouped so you can skim quickly.
Best Western On the River is an informal hotel located in the heart of Hannibal, Missouri, just a short walk from key attractions like the Mark Twain Boyhood Home and Museum and the Mississippi River. Its convenient setting makes it well suited for visitors interested in exploring the area's literary history and riverfront sights. The property’s address at 401 N 3rd St places it within easy reach of local museums and the Mark Twain Cave, with Quincy Regional Airport approximately a 30-minute drive away.
The hotel offers practical amenities including free parking, complimentary breakfast, an indoor pool, and a hot tub. Guest reviews highlight comfortable beds, clean rooms, and friendly staff support, although some note that parking can be tight and housekeeping standards vary. Many guests appreciate the river views available from certain rooms, as well as the easy access to nearby dining and sightseeing.
Facilities cater to a diverse clientele, including LGBTQ+ travelers, with a welcoming atmosphere that balances comfort with straightforward services. The property’s check-in starts at 3 PM, with checkout at 11 AM. While the hotel does not boast upscale luxury, its solid mid-range rating reflects dependable accommodations that meet most guest expectations for a short leisure or business stay.
Nearby attractions such as the Rockcliffe Mansion and the Mark Twain Riverboat offer additional exploration options. For guests who prioritize location and a mix of amenities like a pool and hot tub, Best Western On the River provides a practical base for enjoying Hannibal without elaborate frills.
The short version: what's available day-to-day, and the key practical details most travelers search for.
Reviews from travelers who stayed here in the last 12 months, grouped to help you spot the pattern quickly.
Comfortable beds, hot shower, quiet. Great, friendly service by Tony at the front desk. Housecleaning could be a little better in the bathroom around sink & walls. Breakfast was adequate but hearty. An older hotel but we loved the layout & the easy access. Walking distance to historic Mark Twain district. We could leave our car there since it was off-season. Near restaurants.
Nice hotel, great pool and spa, tasty hot breakfast. Hotel staff were helpful and friendly. Parking is tight, so if you have a big truck or are hauling a trailer, you might struggle - although I'm sure the front desk staff would help you find parking. Tony was obviously proud of the hotel and the city, and had lots of suggestions for things to do. We'll be back!
We were traveling and needed a place to stop on the route to Savannah. The online reviews were good and we got a very reasonable rate. The woman checking us in was friendly (I think.her name was Wendy) and helpful. Our room was very nice, seemed to be newly renovated. Great view of the Mississippi. The pool is lovely and I wish I'd brought a suite. Breakfast was ok, I was able to get some protein to start the day, there were lots of other options. We would definitely stay again.
Booked a handicapped accessible room for one night on Sunday, September 14, 2025. The room had 2 queen beds which were very comfortable. The four pillows, not so much. The bath had a walk in shower which was nice but the shower curtain didn't do it's job and the floor flooded causing a sl I piping hazard. The stool was handicapped height but had no safety grab bars. The free breakfast was generous in volume, but certainly nothing special. The orange juice was the highlight of the meal. The cost of $145 for the night seemed a bit excessive. I might stay there some time in the future, but most likely would look for a different option.
My stay here was for one night but I highly recommend it! The rooms were very clean and nice and spacious! The staff was overly friendly and the area was safe! Also loved all of the Mark Twain stuff around the area!
Clean rooms, spacious bathroom, A/C that blows strong, good WI-FI, and if you get a view of the Mississippi river, the sun rise is breathtaking. Great hot tub that I desperately needed after all the walking I did, and a good hearty breakfast. Friendly hospitality.
Relaxing, comfortable stay in a great Hannibal location! Check-in was quick and welcoming, and the staff stayed friendly and helpful throughout our visit. Our room was very clean, the bed was comfortable, and we slept great. The indoor pool and hot tub were a big bonus, and it was nice having space in the lobby to sit, play games, and unwind. Breakfast hit the spot with solid hot options to start the day. Parking can be a little tight at peak times, but it's manageable. We'd gladly stay here again!
08/14/2025 The room was good. The pillows and bedding were average. The shower head had a surprisingly good height (great for us taller people). The parking situation and being split between two buildings isn't the most ideal, but they do have the option for an indoor and outdoor pool during season. (The indoor pool is open and in the main area of the main building, so the lobby might have a stronger chlorine smell.)
A 2-minute walk from the Mark Twain Boyhood Home and Museum, this informal hotel is 4 minutes' walk from the Mississippi River and 2 miles from Mark Twain Cave.
Curated spots travelers usually pair with a stay in Missouri. Distances are rough real-world times, not straight-line.
1,609 reviews 415 N Main St, Hannibal, MO 63401, United States
497 reviews 1000 Bird St, Hannibal, MO 63401, United States
195 reviews 300 Riverfront Dr, Hannibal, MO 63401, United States
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